CHN 703(O) Unit 1 Chemotherapeutic agents
1. Which type of malaria is
usually fatal?
A.
severe malaria
B. cerebral malaria
C.
a ll of them can be fatal
D.
placental malaria
2. What part of the body do
these malaria parasites feed on?
A.
brain tissue
B.
muscles
C. r ed blood cells
D.
intestinal lining
3. How long
must a malaria parasite grow in its host before infection can be spread to a human being?
A.
two weeks
B. one month
C. a week or more
D.
twenty-four hours
4. What are
the different means of the classification of viruses? Select all the correct options below A) Structure of the viruses
B) Transmission of diseases by viruses C) Biochemical properties of the viruses
D) Host range of the viruses
a)
All the above
b) A, B and C
c) B, C and D
d)
A and B
5. All of the following are the
characteristics of the structure of the virus,
EXCEPT?
A.
The capsid of the viruses is made up of protein
B. The size of viruses may
range from 18 nm to 300 nm
C.
T he outer layer of all
viruses consists of a lipid membrane
D.
Virus consists of either DNA or RNA genome
6. Which of the following is
the largest virus?
A.
Flu virus
B.
S mallpox virus
C. Dengue virus
D.
Polio virus
7. Which of the following does
not contain chlorophyll
A.
Algae
B. Pteridophyta
C.
F ungi
D.
Bryophyta
8. What are the symptoms of
active TB?
A.
Loss of appetite
B.
A ll of the above
C. Weight loss
D.
Night sweats
9. How is TB treated?
A.
Chemotherapy
B. Surgery
C. Antibiotics
D.
A ntiviral medicines
10.
How is TB diagnosed?
A.
Chest X-ray
B.
Skin test
C.
A ll of the above
D.
Sample of sputum
11.
Which of the following drug inhibits the early stage of viral replication??
A.
Methisazone
B.
Idoxuridine
C. A mantadinum
D.
Acyclovir
12.
There are four kinds of malaria that can infect humans. They are all
spread by what?
A.
a mosquito bite
B. a tick bite
C.
a worm in the intestine
D.
a tsetse fly bite
13.
How soon, after infection, will a person feel usually begin to feel ill?
A.
4 days
B. n one of these
C.
6 days
D.
2 days
14.
Which of the following drug is used to treat parasitic disease??
A. 8-Hydroxyquinoline
B. Streptomycin
C. Amphotericin B
D.
Hydroxychloroquine
15.
Who is at risk of developing tuberculosis in this country?
A.
A ll of the above
B. People taking certain medicines
C.
Migrant farm workers
D.
People with HIV
16.
Which of the following drugs inhibit herpes viruses?
A.
Amantadine
B.
Oseltamivir
C. Azidothymidine
D.
A cyclovir
17.
How do you get TB?
A.
Through sexual contact
B. Through blood
C.
Through contaminated food
D.
T hrough the air
18.
Which of the following drug inhibits the creation of glucan in fungel cell??
A.
Butanafine
B. Abafulgin
C.
Micafulgin
D.
Fluconazole
19.
Which of the following drug is used in
leprosy??
A.
E thionamide
B.
Abafulgin
C. Methisazone
D.
Amantadinum
20.
What makes TB hard to diagnose?
A.
Symptoms come and go
B. Symptoms aren't always obvious
C. T he disease may take years to become
D.
active A and B
21.
Which of the following drug is not used in Tuberculosis??
A.
Streptomycin
B. A bafulgin
C.
Ethionamide
D.
Ethanbutol hydrochloride
22.
Once malaria parasites enter a person's blood they then travel to which organ?
A.
stomach
B.
heart
C. kidneys
D.
l iver
23.
Why are drug combinations essential for HIV?
A.
Single drugs are not completely inhibitory
B.
Mutations negate the effect of one drug
C.
Combinations of antibiotics are effective versus TB
D.
T he virus cannot mutate vs a combination
24.
Which season is best for the growth of the fungus?
A.
Winter
B.
R ainy
C. All the above
D.
Summer
25.
which one following is category of leprosy?
A.
Tuberculoid
B. Intermediate
C. Borderline
D.
A ll of above
CHN 703(O) Unit 2 CNS Drugs
1. Which of the following drug
is anticonvulsant drug??
A.
Methisazone
B. P henobarbital
C.
Maprobamate
D.
Streptomycin
2. Which of the following is
neurolaptic drug
A.
C hloropromazine
B.
Isocarboxazid
C. Propronolol
D.
Metoprelol
3. Which of the following drug
is found effective and potent in case of seizur??
A.
Cycrimine
B. M ethsuximide
C. Ethotoin
D.
Ethopropazine
4. Which of
the following drug is not anti anxiety drug but used to combact symptoms of anxiety??
A.
Diazepam
B. M etoprelol
C.
Chloropromazine
D.
Maprobamate
5. Which of the following drug
is not used for Addiction??
A.
Dacarbazine
B.
C hloropromazine
C. Isocarboxazid
D.
Bifemelane
6. An anxiety disorder is:
A.
An emotional state identified by panic
attacks.
B. An emotional condition
classified by excessive checking.
C.
A n excessive or aroused state
characterized by feelings of apprehension, uncertainty and
f ear
D.
Disordered thinking.
7. Antidepressant drugs
inhibits the activity of –
A.
KGP enzyme
B.
N oradreniline
C. CCQ enzymes
D.
E nzymes MAO A & B
8. Anxiolytics are also used for...
A.
All of the above
B. insomnia
C.
M uscle relaxation in specific
neuromusclar disorder
D.
Treatment of epilepsy
9. A long-term
user of cocaine may well develop symptoms of other psychological disorders, such as:
A.
Eating disorders
B.
A ll of three
C. Social phobia
D.
Major depression
10.
Which of the following is not class of anti convulsant?
A.
Succinimides
B.
P heneyclidine hydro chloride
C. Barbiturates
D.
Hydantoin derivative
11.
What mixture of gases are used in anesthesia?
A.
O 2 and N2O
B.
CO2 and N2O
C. O2 and CO2
D. O2, CO2 and N2O
12.
Which of the drug produce rapid, intense emotional swings??
A.
Barbiturates
B.
Ethotoin
C. D imethyltryptamide
D.
Chloropromazine
13.
Hallucinogenic are known as....
A.
Antiolytics
B. Neurolaptic
C. P sychomimetic
D.
Anti-seizur drugs
14.
Which of the following is antiolytics?
A.
Iodoquinol
B.
Reserpine
C. D iazepam
D.
Pipradol
15.
Tranquilizers are used for...
A.
Bipolar disease
B. Tuberculosis
C.
A nxiety
D.
Heart attack
16.
Drugs called Benzodiazepines are used to treat:
A.
Depression.
B.
Schizophrenia.
C. Mood disorders
D.
A nxiety disorders.
17.
Antipsychotics are also known as... A) Neurolaptics.
B) Transquilizers C)Antileprotics
D)Antidepressants
a)
A and C
b)
All the above
c) A and B
d)
A,B and C
18.
Antidepressant therapeutic effects may not seen for two or four weeks:
A.
Serotonin specific reuptake inhibitor
B.
T ricyclic antidepressant
C. Both
D. None
19.
Primary agent used in chronic management of bipolar disorder :
A.
Sufentanil
B.
L ithium
C. Imipramine
D.
Paroxetine
20.
Shortest acting benzodiazepine:
A.
Diazepam
B. Chlordiazepoxide
C. Clonazepam
D.
T riazolam
21.
which of the following neurotransmitter is involved in Parkinson’s disease?
A.
Acetylcholine
B.
Glutamate
C. Dopamine
D.
A ll of above
22. Indicate the drug that induces
parkinsonian syndromes:
A.
C hlorpromazine
B. Diazepam
C.
Triazolam
D.
Carbamazepine
23.
which of the following agents is precursor of dopamine?
A.
Bromocriptine
B.
L evodopa
C. Selegiline
D.
Amantadine
24.
Which of the following antipsychotic drug is typical?
A.
Clozapine
B. Quetiapine
C.
H aloperidol
D.
Olanzapine
25. Indicate the atypical
antipsychotic drug:
A.
Haloperidol
B. C lozapine
C.
Thioridazine
D.
Thiothixene
CHN 703(O) Unit 3 Cardiac Drugs & Diuretics
1. Adverse effects associated
with thiazide diuretic use:
A. Gout
B.
Potassium depletion
C. B oth
D.
None of above
2. Adverse effects associated
with loop diuretics:
A. Potassium deplation
B. Ototoxicity
C.
Gout
D. A ll of above
3. Clinical use of clonidine:
A. Analgesic
B.
Antihypertensive
C.
B oth
D. Neither
4. Antihypertensive drug effect
inhibited by imipramine or cocaine:
A. Metoprolol
B.
Proponolol
C. G uanethidine
D. Triamterene
5.
Aspirin
A. Reduces mortality after a
myocardial infarction
B. Must be discontinued if the
patient complains of dyspepsia
C.
Is effective in primary prevention of myocardial infarction
D.
Prevents Stroke
E. Gives additive benefit when
combined with warfarin after pulmonary embolism
6. Beta blockers
A. Reduce angina by reducing
myocardial oxygen demand
B. Are contraindicated in heart failure
C. Are contraindicated in
chronic obstructive airway disease
D.
Reduce left ventricular hypertrophy
E. Reduce the incidence of
sudden cardiac death after myocardial infarction
7. Antihypertensive drugs
A. R educed evaluated blood pressure
B. Induces evaluated blood
pressure
C.
A & B both
D. None of above
8. Symptoms of hypertension
A. High blood pressure
B.
Chest pain
C. Severe headache
D. A ll of above
9. which of the following is
not Antihypertensive Drugs?
A. Captopril
B. Ethacrynic acid
C.
Captopril
D. L idocaine
10.
Antiarrhythmic drugs
A. U sed to treat abnormal heart rhythms
B.
Used to reduce blood pressure
C. All of above
D. None of above
11.
Symptoms of Arrhythmia
A. Chest pain
B.
Dizziness
C. Shortness of breath
D. A ll of above
12.
Example of Antiarrhythmic drugs are
A. Lidocaine
B. Procainamide
C.
Amiodarone
D. A ll of above
13.
Antihyperlepidemic drugs
A. Used in the treatment of
high levels of fats
B.
Used in the treatment of high cholesterol
C.
A & B
D. None of above
14.
symptoms of hyperlipidemia
A. Chest pain
B.
Cramps
C. Sores on the toes
D. A ll of above
15.
which of the following is not examples of Antihyperlipedemic drugs?
A. Nicotinic Acid
B. Clofibrate
C.
Evilocumab
D. C aptopril
16.
Antianginals are
A. U sed in the treatment of
angina pectoris
B. Used in the treatment of hypertension
C. Used in the treatment of hyperlipidemia
D. Used in the treatment of leprosy
17.
Symptoms of angina pectoris
A. Chest pain
B. Heaviness
C.
Squeezing
D. A ll of above
18.
which of the following is example of antianginals agents?
A. R anolazine
B.
Nicotinic acid
C.
Captopril
D. Ethacrynic Acid
19.
Diuretics are _
A. Increase the amount of urine
B.
Promote the removal from the body of excess water and salt
C. A & B
D. None of above
20.
Symptoms of diuresis
A. Low sodium levels
B. Muscle cramps
C.
Thirst
D. A ll of above
21.
which of the following is not class of
diuretics?
A. Mercurial
B. Non mercurial
C.
A & B
D. None of above
22.
Example of Osmotic Diuretics
A. U rea
B.
Aspirin
C. Thiazide
D. Chlorthiazide
23.
Example of Acidic Diuretics
A. A mmonium Chloride
B.
Ammonium Acetate
C. Aluminum Chloride
D. Calcium Chloride
24.
Furosemide is example of
A. S ulphonyl benzoic acid
derivative
B.
Phenoxyacetic acid derivative
C. Thiazide derivative
D. Hydroxythiazide derivative
25.
Disulphamide is example of
A. C Ase Inhibitor
B. Phenoxyacetic acid derivative
C.
Thiazide derivative
D. Hydroxythiazide derivative
CHN 703(O) Unit 4
Antidiabetic, Hypertensive and Anticancer Drugs
1. High blood pressure is the
main cause of which of these?
A.
Cancer
B. S trokes
C.
Congestive heart failure
D.
Diabetes
2. Which of these can increase
your risk of high blood pressure?
A.
Obesity
B.
Smoking
C. A family history of high
blood pressure
D.
A ll of the three
3. What is the most common
symptom of high blood pressure?
A.
F atigue
B. Racing heartbeat
C. High body temperature
D.
It has no symptoms that you notice
4. At what age should you have
your first screening for high blood pressure?
A. 1 8
B.
30
C. 50
D. 16
5. In which age group of men does
the risk for high blood pressure go up?
A. 6 0
to 69
B. 70 to 79
C.
50 to 59
D. 40 to 49
6. At what point is blood
pressure considered "high"?
A.
210 over 120
B. 120 over 80
C.
1 30 over 80
D. 140 over 90
7. What can you do to control
high blood pressure?
A.
A ll of the above
B.
Take the blood pressure medicine prescribed by your doctor
C. Get to and stay at a healthy
weight E
D.
exercise regularly
8. Why does reducing how much
salt you eat help prevent high blood pressure?
A.
I t helps keep your heartbeat steady
B. It allows vessels to relax
C.
It raises levels of HDL ("good") cholesterol
D.
It reduces fluid buildup in the body
9. Which of these contribute to
high blood pressure?
A.
Getting a lot of vitamin C
B. A ll of the above
C.
Getting a lot of calcium
D.
Drinking a lot of alcohol
10.
The numbers in blood pressure reading:
A.
V ary, depending on the time
of day your blood pressure is checked
B. Get lower with high levels
of stress
C.
Are the same for people of the same age and weight
D.
Stay the same throughout the day
11.
Excessive use of tolbutamide will lead
to
A.
Diarrhea
B.
P rolonged hypoglycemia
C. Tolerance to alcohol
D.
Acidosis
12.
Preferred route of insulin is
A.
Oral
B. S ubcutaneous
C. Sublingual
D.
Enteric coated tabs
13. Longest acting insulin is
A.
Insulin zinc suspension
B. Isophane insulin
C.
Globin zinc insulin
D.
p rotamine zinc insulin
14.
Normal blood glucose level for non-diabetic should be
A.
B etween 3.9 and 7.1 mmole/L
B. Between 1.0 and 3.8 mole/L
C.
Between 7.5 and 10.0 mmole/L
D.
None of above
15.
Diabetes is also known as
A.
H ypoglycemia
B. Hypertension
C. Hyperglycemia
D.
None of above
16.
which of the following is not type of
diabetes?
A.
Diabetic Insipidus
B. Diabetic mellitus
C.
N one of above
D.
All of above
17. Insulin is
A.
P olypeptide
B. Polysaccharide
C.
Polyamide
D.
Polyester
18. Insulin contains
A.
0 .3 to 0.6 % zinc
B. 0.7 to 0.9 % zinc
C.
0.1 to 0.2 % zinc
D.
1.0 to 1.5 % zinc
19.
which of the following is not type oral hypoglycaemic agents?
A.
Sulphonyl ureas
B. Non sulphonyl ureas
C.
Bisguanidine
D.
i nsulin
20.
Anticancer drugs also known as
A.
Anti-neoplastic agent
B.
Anti-tumour drugs
C. A & B
D.
None of above
21.
Which of the following is cancer causing agents?
A.
Tobacco
B. Ionizing radiation
C. Viral and bacterial infection
D.
A ll of above
22.
Methotrexate prevents synthesis of DNA and RNA by
inhibiting the production of nucleic
acids. Drugs such as methotrexate that interfere with vital cellular functions
by mimicking compounds in cells are called
A.
Genotoxic drugs
B.
A ntimetabolites
C. Spindle inhibitor
D.
Angiogenesis inhibitors
23.
Radiation is used to
A.
Destroy healthy tissues surrounding a tumour, preventing the conversion
of those cells
B. K ill cancer cells directly
via the induction of DNA damage and cell death
C. Prevent cancer growth by
destroying nearly blood vessels
D. Force normal cells to kill nearby cancer cells
24. Side effects of chemotherapy
A.
Nausea
B. Hair loss
C.
Increased susceptibility to infection
D. A ll of above
25. Different cell types may be identified by receptors located on their surface. _ therapies take advantage of this to deliver radiation to cancer cells.
A.
Local radiations
B.
Radiation induced gene
C.
Receptor targeted radiation
D.
A uger emitting radiolabelled molecular
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